Author's response to reviews Title:Perilla Extract improves GI health in a randomized placebo controlled double blind human study Authors:

Author's response to reviews Title:Perilla Extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study Authors:

Suggest you state that the aim was to investigate rather than demonstrate, as you have no idea of the outcome prior to the study. Was implemented Methods section of Abstract: You need to state these were healthy subjects with GI discomfort and reduced bowel movements. Was implemented Results section of Abstract: typo 2nd sentence: imoroved (should be improved) Was implemented Page 5 IRBspell ou...

Author's response to reviews Title: Transglucosidase improves the gut microbiota profile of type 2 diabetes mellitus patients: A randomized double-blind, placebo-controlled study Authors:

Title: Transglucosidase improves the gut microbiota profile of type 2 diabetes mellitus patients: A randomized double-blind, placebo-controlled study

Author's response to reviews Title: Essential fatty acids for premenstrual syndrome and their effect on prolactin and total cholesterol levels: a randomized, double blind, placebo-controlled study Authors:

Author's response to reviews Title:Utility of the sore throat pain model in the multiple-dose assessment of an acute analgesic: a double-blind, randomized, placebo-controlled study of flurbiprofen 8.75 mg lozenges Authors:

Title:Utility of the sore throat pain model in the multiple-dose assessment of an acute analgesic: a double-blind, randomized, placebo-controlled study of flurbiprofen 8.75 mg lozenges

Letter to editor: the critical appraisal of “efficacy of licorice extract in the treatment of melasma: a randomized, double-blind, lacebo-controlled clinical trial”

This is a letter to editor criticizing the paper entitled “Efficacy of licorice extract in the treatment of melasma: A randomized, double-blind, placebo-controlled clinical trial”. We discuss some methodological points on external and internal validity of results. The paper suffers from lack of detailed information on sample size and power calculation to make sure generalisability of results to...